MatSolCa (MSC) is a useful Materials informatics tool as Solubility Calculator with in-phase deep neural network (ip-DNN). MSC calculates Hansen's solubility parameters (HSPs), Hildebrand's solubility parameter (SP) & LogP from measured data, such as 1D-H/C-NMR data, density & refractive index. We have expectations that MSC supports effective and agile development for materials, paints, food, drug discovery, etc.